OptiNOs Lab Research: mTOR Signaling and Nitric Oxide in Cells
In cell studies, OptiNOs activated mTOR signaling, a pathway that regulates muscle protein synthesis, and increased nitric oxide production in human blood vessel cells.
Summary
Laila Nutraceuticals tested OptiNOs in several cell models. It activated mTOR signaling in skeletal muscle cells, increased nitric oxide production in human blood vessel cells, and increased ATP production in muscle cells.
Context Note
Lab study run by the ingredient maker. Lab results show what happens in cells, not in people.
Study breakdown
Why this study was done
Laila Nutraceuticals ran cell studies to understand how OptiNOs might work in muscle and blood vessel cells.
How it was run
OptiNOs was added to skeletal muscle cells and human primary endothelial (blood vessel lining) cells at concentrations from 1 to 1,000 ng/mL.
What they found
- mTOR and p70S6K, two proteins in the pathway that regulates muscle protein synthesis, were activated in skeletal muscle cells.
- Nitric oxide production rose in human endothelial cells through eNOS activation.
- ATP production and muscle cell formation markers rose in muscle cell cultures.
Limitations
The slides give no statistics or repeat counts for most results, and the muscle cell line is not always named. It has not been published or peer reviewed.
What it means in practice
These results show possible ways OptiNOs works at the cell level. The human strength results come from the separate trial in resistance-trained men.
Study Type
Lab Study
Published
2019
Unpublished manufacturer data
Participants
Not applicable, skeletal muscle and endothelial cell cultures
Dose Studied
1 to 1,000 ng/mL in cell culture
Health Focus
No items found.
Ingredients
OptiNOs
Frequently Asked Questions
Are these formulas safe to take with medication?
That depends on the specific medication and formula. A few, like blood thinners with CurQLife or blood pressure medication with MaxiNOs, are worth a direct conversation with your doctor first. Check each formula's own FAQ section for specifics, or ask your health coach.
Do all four formulas have the same level of research behind them?
No, and we'd rather be upfront about it. Bacopa, the plant in BacoZest, has published human studies, though they used other bacopa extracts. OptiNOs and MaxiNOs each have human studies sponsored by their maker, Laila Nutraceuticals, which haven't been published in a journal. CurQLife's research is still early, from lab and animal studies, and we label it that way.
Which formula is right for me?
It depends on what you're building your routine around. BacoZest is built around bacopa, which is studied for memory.* OptiNOs supports strength and muscular endurance alongside resistance training.* MaxiNOs was studied for healthy blood vessel function.* CurQLife's research is still at the lab stage. Your health coach can help you pick a starting point.
Are these ingredients safe?
All four are built around plant extracts. OptiNOs was reported as well tolerated in its human study, and published bacopa studies reported no serious side effects. CurQLife's safety data so far comes from lab and animal testing. Check with your doctor first if you're pregnant, nursing, on medication, or managing a health condition.
Why are patented ingredients more expensive?
Because the patented ingredients behind our four formulas went through dedicated research, and research costs real money. A generic curcumin or bacopa supplement hasn't been tested in the form you get from us. You're paying for an ingredient with research behind it, not just a label.
What makes The Collection different from other brands?
Generic ingredients often haven't been studied in the specific form you're buying. Our four core formulas use patented ingredients, and we show you the research behind each one, including where it's still early.
How long until I notice results?
It depends on the formula. In its study, MaxiNOs blood vessel response was higher than placebo 2 to 3 hours after the first dose.* OptiNOs and bacopa were studied over 6 and 12 weeks of daily use, so give them time. CurQLife is meant to be taken daily.
Can I take all four together?
Yes. BacoZest, OptiNOs, MaxiNOs, and CurQLife are built for different goals, and none of them contain stimulants. They haven't been studied together, so ask your health coach how to fit them into your routine.
