CurQLife Plus: COX and 5-LOX Enzyme Activity in a Lab Assay
CurQLife Plus cut COX enzyme activity in half at 19.9 µg/mL and 5-LOX activity in half at 24.6 µg/mL in a lab assay.
Summary
Laila Nutraceuticals tested CurQLife Plus, a 1:1 blend of turmeric extract and BNRE, against two enzymes in the body's inflammatory response. COX activity fell by half at 19.9 µg/mL and 5-LOX activity fell by half at 24.6 µg/mL.
Context Note
Lab study run by the ingredient maker. Lab results show what happens in a test tube, not in people.
Study breakdown
Why this study was done
COX and 5-LOX are two enzymes that drive the body's inflammatory response, each on its own pathway. Laila Nutraceuticals, the maker of CurQLife, tested whether its 1:1 blend of turmeric extract and BNRE affects both.
How it was run
A cell-free enzyme assay. CurQLife Plus was added at five concentrations, from 3.125 to 50 µg/mL, and enzyme activity was measured at each one.
What they found
- COX activity fell by half at 19.9 µg/mL (the IC50).
- 5-LOX activity fell by half at 24.6 µg/mL.
- Both enzymes were affected by the same blend.
Limitations
This is test-tube data from the ingredient maker. The report does not give the number of repeats, error bars, statistics or which COX type was tested. It has not been published or peer reviewed.
What it means in practice
The result shows how the blend behaves against these enzymes in a lab. It has not yet been tested in people.
Study Type
Lab Study
Published
2015
Unpublished manufacturer data
Participants
Not applicable, cell-free lab assay
Dose Studied
3.125 to 50 µg/mL in a test tube
Health Focus
No items found.
Ingredients
CurQLife
Frequently Asked Questions
Are these formulas safe to take with medication?
That depends on the specific medication and formula. A few, like blood thinners with CurQLife or blood pressure medication with MaxiNOs, are worth a direct conversation with your doctor first. Check each formula's own FAQ section for specifics, or ask your health coach.
Do all four formulas have the same level of research behind them?
No, and we'd rather be upfront about it. Bacopa, the plant in BacoZest, has published human studies, though they used other bacopa extracts. OptiNOs and MaxiNOs each have human studies sponsored by their maker, Laila Nutraceuticals, which haven't been published in a journal. CurQLife's research is still early, from lab and animal studies, and we label it that way.
Which formula is right for me?
It depends on what you're building your routine around. BacoZest is built around bacopa, which is studied for memory.* OptiNOs supports strength and muscular endurance alongside resistance training.* MaxiNOs was studied for healthy blood vessel function.* CurQLife's research is still at the lab stage. Your health coach can help you pick a starting point.
Are these ingredients safe?
All four are built around plant extracts. OptiNOs was reported as well tolerated in its human study, and published bacopa studies reported no serious side effects. CurQLife's safety data so far comes from lab and animal testing. Check with your doctor first if you're pregnant, nursing, on medication, or managing a health condition.
Why are patented ingredients more expensive?
Because the patented ingredients behind our four formulas went through dedicated research, and research costs real money. A generic curcumin or bacopa supplement hasn't been tested in the form you get from us. You're paying for an ingredient with research behind it, not just a label.
What makes The Collection different from other brands?
Generic ingredients often haven't been studied in the specific form you're buying. Our four core formulas use patented ingredients, and we show you the research behind each one, including where it's still early.
How long until I notice results?
It depends on the formula. In its study, MaxiNOs blood vessel response was higher than placebo 2 to 3 hours after the first dose.* OptiNOs and bacopa were studied over 6 and 12 weeks of daily use, so give them time. CurQLife is meant to be taken daily.
Can I take all four together?
Yes. BacoZest, OptiNOs, MaxiNOs, and CurQLife are built for different goals, and none of them contain stimulants. They haven't been studied together, so ask your health coach how to fit them into your routine.
